Markets collapse as crude oil extends slide

The continued decline of crude oil prices along with concerns about the Chinese economy sent the markets plunging to a sharply lower close with the Dow collapsing 315 points to 17,280. Nasdaq plummeted 54 points to 4,653.

On the upside

Oncothyreon (Nasdaq: ONTY) reported positive preliminary data from two ongoing Phase 1b studies of ONT-380 to treat metastatic breast cancer.

China HGS Real Estate (Nasdaq: HGSH) reported sharply higher full year earnings and revenue.

Shares of Calithera Biosciences (Nasdaq: CALA) continued to soar.

On the downside

Shares of Midstates Petroleum (NYSE: MPO) continued falling.

Esterline Technologies (NYSE: ESL) fell to a loss for the fourth quarter.

Heritage-Crystal Clean (Nasdaq: HCCI) priced its public offering of 3.1 million share of common stock at the discounted price of $10 per share.

In the broad market, declining issues outpaced advancers by a margin of nearly 4 to 1 on the NYSE and by nearly 5 to 2 on Nasdaq. The broader S&P 500 plunged 33 points to 2002. Bitcoin rose $7 to $351.
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