Crude oil drops, markets close lower

The markets closed lower with the Dow falling 41 points to 17,581 as crude oil prices dropped. Nasdaq slipped 4 points to 5,030.

On the upside

Pacira Pharmaceuticals (Nasdaq: PCRX) swung to a greater than expected profit for the third quarter as revenue rose.

Ctrip.com (Nasdaq: CTRP) will acquire a 445% stake in Qunar Cayman Islands (Nasdaq: QUNR) in a stock swap deal with Baidu (Nasdaq: BIDU).

Isis Pharmaceuticals (Nasdaq: ISIS) will host a webcast on Tuesday, November 3 to review ISIS-TTR data that was presented at the 1st European Congress of Hereditary ATTR Amyloidosis and provide a Phase 3 development plan update.

On the downside

Hi-Crush Partners (NYSE: HCLP) fell to a loss for the third quarter as revenue dropped and suspended its quarterly dividend.

Peabody Energy (NYSE: BTU) widened third quarter losses as revenue fell and warned that coal demand will continue to drop.

Knowles (NYSE: KN) widened losses for the third quarter.

In the broad market, declining issues outpaced advancers by a margin of more than 3 to 1 on the NYSE and by nearly 5 to 2 on Nasdaq. The broader S&P 500 lost 5 points to 2,065. Bitcoin gained $9 to $292.

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