Endotoxemia Market: Global Industry Analysis and Forecast 2016 - 2024

New York, NY -- (SBWIRE) -- 05/05/2016 -- Endotoxemia is defined as the presence of endotoxins in the bloodstream, resulting in hemorrhages, necrosis of the kidneys and septic shock. Endotoxins are a major component of the cell wall of gram negative bacteria present in the form of lipopolysaccharides and infect both human beings and animals, majorly horses. Endotoxemia is responsible for powerful clinical manifestations involving pathogenic Gram-Negative (GN) bacteria such as meningococcemia, meningitis and Waterhouse syndrome. Alcoholic hepatitis is said to occur when endotoxemia infects intestine leading to the development of small bowel bacterial overgrowth syndrome and rapid increased intestinal permeability. Studies have noted that purified endotoxin from Eschericha coli and Enterobacter cloacae contribute to increased incidence of obesity and insulin resistance phenotypes in patients. Research studies have found that endotoxemia is not detectable for at least 20% and up to 50% of patients with GN bacteremia. Moreover, the relevance of endotoxemia to prognosis is dependent on the co-detection of GN bacteremia, and the underlying mortality risk in the study population. The unmet opportunity for usage of endotoxins in wide variety of indications is expected to push pharmaceutical companies to develop medicines with better efficacy.